Resins
Solid phase chemistry is attracting much attention worldwide with many applications being realised and marketed by various companies and academia. As a result, solid supports have attracted much attention. There are now many examples in use with many applications in industry. Some examples of resins include Tentagel, CLEAR, PEG, PEG-polystyrene composites, polyamides, cotton, carbohydrates, controlled pore silica glass.
This field is huge, with applications being found in catalysis, combinatorial chemistry, ion exchange resins and purification procedures. Resins can be used for the synthesis of peptides, oligonucleotides, peptoids, and other analogues. Combinatorial chemistry is a method that has evolved to satisfy the requirements of these chemistries. Ion exchange resins are frequently used to aid the purification of mixtures, while gel permeation resins are used to differentiate molecules according to their relative sizes. Purification has been achieved by the chemical anchoring of quenching agents to the solid support. |