|
| Former Graduate Students |
Dr. Lorraine Baldock |
Lorraine was born in Essex in 1974. Upon finishing her
A levels she studied accountancy for a year before coming
to University in Southampton, where she obtained a double
honours in Chemistry and Biochemistry. During her third
year she worked for Mark Bradley on the solid phase synthesis
of Kukoamine and other polyamines. Her fourth year was spent
in the biochemistry department working for Dr Ram Sharma
on the solid phase synthesis of Topoisomerase II inhibitors,
for use in chemotherapy. She joined the group in September
1998 and did an MPhil under the supervision of Prof. Mark
Bradley and Dr David Harrowven. When not in the lab she
enjoys ballroom and Latin American dancing, scrambling,
rock-climbing and walking.
|
Dr. Andrea Basso
|
Andrea Basso was born in Genoa (Italy) in 1971, he graduated
(Hons.) in Organic Chemistry in December 1995 at the Università
degli Studi di Genova. The subject of his thesis was "Experimental
and theoretical work towards the synthesis of lactendiynes",
a new class of cyclic enediynes fused with a ß-lactam
moiety; this work was carried out under the supervision
of Prof. G. Guanti. In 1996, thanks to EEC funds, he spent
four months at the University of Halle (Germany) in the
lab of Prof. M.E. Maier, working on a project about Dynemicine
analogues.
On his return to Genoa he continued working with Guanti's
group on asymmetric reactions on bis-(hydroxymethyl)propanoates.
In October 1996 he started his civil service as a conscientious
objector and spent one year in the Comunita' OdC Caritas
"La Locomotiva" ( W. Paolo Bruzzo!), working with
homeless people.
In October 1997 he joined Prof. Bradley's group, where at
present he is a Ph.D. student. The subject of his research,
sponsored by Glaxo Wellcome, is "High Loading Beads
for Single Bead Screening in Combinatorial Chemistry."
Other interests:
He is a member of the Volleyball Team of the University
of Southampton; he is also a member of the Athletic Union
and of the Catholic Society. He likes skating, cycling,
swimming
He is a continental definitely!
|
Dr. Nathalie Bouloc |
Nathalie Bouloc was born in 1973 in Montargis, France.
She started her undergraduate studies at the University
of Orleans where she obtained a "diplome universitaire
de technologie" (DUT) in chemistry (technician diploma
equivalent to a HND in chemistry) than obtained an Engineer
Diploma at the National School of Chemistry of Montpellier
in 1996. In 1995, as part of the Erasmus program, she joined
the group of Prof. M. Bradley where she obtained a Master
of Philosophy in organic chemistry working on photocleavable
linkers. Her PhD involved working on novel peptide like
structures.She is now doing a post doc under the expert
supervison of Tony Barret at Imperial College, London.
|
Dr. Jenny Britton |
Jenny first came to Southampton to do an
undergraduate degree in Chemistry with Pharmacology. After
completing a final year project for Mark Bradley she liked
combinatorial chemistry so much she decided to stay and do
a PhD working on the development of new safety-catch linkers
sponsored by British Biotech, Oxford. Jenny is now working
as a clinical research associate at PRA International, Reading
where she is involved in the conduct of clinical trials in
a variety of phases and therapeutic areas. She delights in
reading, loves the cinema, and also enjoys playing squash.
E-mail: brittonjennifer@praintl.com
|
Dr. Sarah Burrage |
Sarah graduated from Southampton University with an honours
degree in Chemistry with Biochemistry in July 1995. She
has finished her Ph.D. working on the lantibiotic subtilin.
Sarah now works as secondary school science teacher..
Her hobbies include ballroom dancing, aerobics and racket
sports. She has also played the cello for many years.
|
Dr. Marianne Cardno |
Marianne was born in Edinburgh in 1971. She
graduated with an honours degree in Chemistry from the University
of Glasgow in July 93. She joined the then embryonic Bradley
Group in Oct 93 where she studied for her Ph.D. on the Biomimetic
Synthesis of Lantibiotics. On completing her Ph.D. in July
97 she joined Novartis Pharmaceuticals in Horsham, West Sussex
where she now works as a Clinical Pharmacology Scientist.
Marianne is involved in Phase I clinical trial management
and enjoys much travel both in the UK, Europe and beyond.
Outside work, she enjoys swimming, dancing, golf, theatre
and wine tasting drinking!
E-mail: marianne.cardno@novartis.pharma.com
|
Dr. Bryan Egner |
Bryan was born a farmers son in Edinburgh
in the summer of '72. Following his undergraduate studies
at Southampton he stayed on to join the Bradley group in October
of '93, working with the solid phase synthesis of the depsipeptide
antibiotics Lysobactin and the Katanosins. The advent of "combinatorial
chemistry" took his interest and subsequently diverted
his attentions to, amongst others, the development of rapid
mass spectrometry analysis of solid phase reactions. Well
versed in solid phase combinatorial techniques Bryan left
for a Post Doc. position in Sweden (setting a trend) with
Astra Hässle to develop various library syntheses. His
love for Sweden along with the exciting opportunities presented
by Astra Hässle meant in April of 1998 he signed on as
a permanent employee within the combinatorial chemistry group.
Other than chemistry his activities include participation
in most sports and learning Swedish (and he thought his Finals
was the hardest thing he'd ever do!)
Email: bryan.egner@hassle.se.astra.com
|
Dr. Sunil Rana
|
Sunil Rana was awarded Upper-Second Class
Honours in each of Chemistry and Biochemistry in his Double
Honours Degree at the University of Southampton, England,
UK, and then in 1997 accepted a place on the Post Graduate
course. Sunil is now a year 3 Ph.D. student under the supervision
of Professor Mark Bradley (University of Southampton) and
Dr. Peter White (Calbiochem-Novabiochem UK Ltd.). His project
involves the synthesis of novel resins and polymer supported
reagents and realizing their applications to the field of
organic and combinatorial chemistry. He has gained experience
in peptide, polymer, combinatorial, catalytic and heterocyclic
chemistry. His project necessitates the use of many forms
of microscopy (optical, scanning tunnelling, and transmission
electron and X-ray) and he is experienced in analysis by these
and the more conventional chemistry tools. Sunil always has
a number of dodgy deals on-the-go!
|
Dr. Helen Russell |
Helen did her first degree in Chemistry with
Biochemistry at the University of Southampton. After her graduation
in 1996, she did her PhD for Prof. Mark Bradley in collaboration
with Zeneca pharmaceuticals. She conducted research into new
safety-catch linkers for combinatorial chemistry. She now
works for Smith & Nephew. When not doing chemistry, she
enjoys skiing, squash and badminton. She also went back to
school and completed a GCSE in Italian.
|
Dr. Helen Smith |
Helen started working for Mark for her final
year undergraduate project which led to both a 10 week placement
sponsored by the Royal Society, followed by her PhD. She spent
her 3 years developing novel solid phase polyamine linkers
and using them to produce several libraries of potential inhibitors
of the parasitic enzyme trypanothione reductase (TR). After
trying a bit of molecular biology and a fair bit of biochemistry,
she used recombinant TR to screen my libraries both in solution
and on the solid phase. 3 different screening techniques identified
the same potent enzyme inhibitors. She enjoyed her time at
Southampton a great deal and found enough time for other more
mundane pastimes ranging from the Chaplaincy to skydiving
(which she fully recommends taking up whilst doing a PhD...!).
After her PhD she travelled for a couple of months to Australia
and Malaysia and returned to start a job with British Biotech
in their lead validation team.
E-mail: smithh@britbio.co.uk
|
|
Dr. Vinay Swali |
Vinay Swali started his BSc. Degrees in Chemistry
and Biochemistry at Southampton University in 1991. During
this time he studied a broad range of subjects including physiology,
pharmacology, genetics and molecular biology. The undergraduate
course also provided an opportunity to carry out research
work. In 1994 he undertook a project entitled "Solid
phase synthesis of starburst dendrimers" under the supervision
of Prof. Mark Bradley. The following year saw a move to the
laboratory of Prof. M. Akhtar, working on the development
of new anti-bacterial agents based upon B/PI (bactericidal/permeability
inducing protein).
In 1995 he began a PhD under the supervision of Prof. Mark
Bradley entitled "Combinatorial libraries based on lantibiotic
templates". This project has seen him gain considerable
experience in solid phase organic synthesis, peptide chemistry,
synthesis of novel amino acids, dendrimer chemistry as well
as a large range of analytical techniques for both solid and
solution phase reaction monitoring, In 1997 he completed a
three month industrial placement at SmithKline Beecham Pharmaceuticals,
Harlow as part of a PhD CASE collaboration.
Outside the laboratory his interests are mainly sports related.
He instructs karate and self-defence at the University, as
well occupying positions on the Shotokai Karate Committee
and the Athletic Union Martial Arts Committee. His other hobbies
include football, squash, weight training, running, swimming
and playing the guitar.
|
Dr. Hitoshi Mizomoto
|
Hitoshi was born in Hyogo (Japan) in 1975, he graduated
from Osaka University in March 1997 with a BSc and then
did a MSc in Organometallic Chemistry. He worked for Asahi
Kasei Corporation for three years before joining Prof. Bradley’s
group in February 2002. He has been studying for a PhD on
a project concerning the synthesis of biocompatible polymer
library. He enjoys travelling with friends.
|
| Dr. Yu Cheng Luan |
Yu Cheng was born in Guangdong, China in
1978. He obtained his B.Sc degree in Chemistry at Jilin University
in 1999. Since then, he has worked as a research assistant
at Changchun Institute of Applied Chemistry, Chinese Academy
of Sciences, for about 2 years. There he undertook some projects
on polymer physics and material science. In Mar. 2002, he
joined the Bradley group to undertake his PhD degree. His
topic is related to the synthesis and application of mesoporous
materials. Yu Cheng enjoys travelling in his spare time.
____________
|
Dr. Carole Bruckler
|
Carole was born in ickle Luxembourg in
1979, which left for the UK in 1998 to study for her undergraduate
degree at the University of York, from where she graduated
in 2002 with an MChem degree in Chemistry, Life systems &
Pharmaceuticals. During that time she also did a one year
placement at GlaxoSmithKline in Pharmaceutical Development.
She joined the Bradley group in October 2002 and has been
working on site specific labelling of proteins and peptides
as well as working towards a solid-supported phosphorylating
agent for nucleosides. Her work is supported by the BBSRC,
Amersham Biosciences and the University of Southampton. In
her spare time she enjoys socialising, playing pool (haha),
sailing, mushroom picking and cycling to work every day!!
|
| Dr. Toby Cull |
Toby graduated from Southampton University
in June 2002 with a Master in Chemistry. As part of the course
he completed a 6 month placement with Permabond in which he
carried out work on improvement of epoxy resins. Toby is currently
continuing his education at Southampton studying for a PhD
with Professor Mark Bradley. His project involves development
of a combinatorial approach to liquid crystal synthesis and
screening, in partnership with Merck. Out of the lab Toby
is a keen canoeist and enjoys throwing himself down waterfalls
in a small lump of plastic. He also enjoys eating and socialising!
___________
|
| Dr. Romain Najman |
Romain was born in Paris in 1977. He moved to study chemistry
in Rennes at the ENSCR (Ecole Nationale Superieure de Chimie
de Rennes). During this period, he specialised in organic chemistry
and also spent some time working in the industry, e.g. Wallac
Oy in Finland and Serono Pharmaceutical Research Institute in
Switzerland for a whole year. He spent one year as an Erasmus
exchange student at the University of Hull where he obtained
an MChem degree in addition of graduating from the ENSCR. He
then arrived in Southampton in October 2002 for a PhD, under
the supervision of Professor Bradley and funded by Polymer Laboratories,
working on a new form of resin handling : the StratoSpheres
Plugs. Romain especially likes broadening his horizons and therefore
loves travelling to meet new people and cultures. He also enjoys
a lot skiing and mountaineering, watching movies, playing team
sports (especially football and volleyball), going to gigs (sigh
Placebo - Paleo Festival 2001 !) and of course visiting his
friends, wherever they are !
___________ |
| Dr. Anaïs Ronot |
Anaïs was born in 1978 in Guadeloupe
and spent her childhood in North West Africa. She studied
at ESCOM (Ecole Supérieure de Chimie Organique et Minérale)
in Cergy Pontoise, France, where she specialised in organic
chemistry. During her course, she spent one year working at
Kodak in Harrow, UK on masking coupler, ADAs and sensitising
dyes. Attracted by working in combinatorial chemistry, she
is now undertaking a PhD under the supervision of Professor
Mark Bradley which involves the modification of pigment particles.
She hates watching football, but she likes climbing, caving,
sailing, skiing, travelling and of course eating (wt: 198
kg).
___________ |
| Dr. Guilhem Tourniaire |
Guilhem was born in Toulouse in 1978. He first obtained a
technician degree of Chemistry from the University of Montpellier.
This course included a 4 month industrial placement, during
which he discovered the north west of England working for Unilever
(Port Sunlight, Merseyside). In 1999, Guilhem then decided to
move to Kingston University where he obtained his MChem in Chemistry
with a year long industrial placement at BASF (Gosport, Hampshire).
He joined the Bradley group in October 2002. His research project
is orientated towards the development of new screening methods
for bio-compatible polymer libraries. In his free time, Guilhem
enjoys travelling, playing percussion, and of course going out
with friends. |
Jing Ma |
Jing was born in Changchun city,Northeast China In 1999 she
finished her undergraduate degree in Wuhan university and
worked at State Key Lab of Electroanalytical Chemistry, Changchun
Institute of Applied Chemistry,
Chinese Academy of Sciences.In 2002,she visited chemistry
department of southampton University.She joined the Bradley
group in April 2005.She has two research projects.One is highthrough
measurement,the other one is modification of glass surface.
In her free time, jing enjoys travelling, playing badminton
and reading .
|
Chiung Ying Ou Yang
|
Ouyang was born in Chia-yi , Taiwan . She
got her undergraduate degree in chemistry at National Sun
Yat-Sen University (the most beautiful campus with grand sea
view and mountain) in Taiwan . Afterwards, she got her MSc
degree in organic chemistry in the University of Edinburgh
. She joined the Bradley Group in January 2007 to work on
the project about the development of a range of cellular delivery
reagents for the delivery of drugs, functional proteins and
RNAi based molecules into cells. In her spare time, she enjoys
listening to music and travelling.
|
Dr. Christophe Portal
|
Christophe was born in Nîmes, South
of France. He got a chemical engineering diploma from the
ENSSPICAM (National Higher School of Chemistry of Marseilles)
in 2003, as well as a DEA (MChem) in molecular chemistry and
bioactive molecules. During his time at the ENSSPICAM, he
spent plenty of time taking "apéros" on the
"Vieux Port" (happy hours!!), and trying to make
people dance as the official DJ of the school. He also filled
himself up with sun (in south of France as well as in California
during a 4 month placement in a biotech in San Diego ). He
likes playing guitar, listening to music, going to gigs, running
(well, when it doesn't rain or hail) and cooking. Christophe
took his PhD studies in the Bradley group from january 2004
to January 2007. His project was about the development of
quantitative molecular tag to be able to quantify mixtures
of compounds using ESI+/MSD as the sole analytical tool. The
technique was applied to monomer reactivity profiling, Hammett
parameter assessment, protease kinetic assessment. Christophe
is now working as a synthetic chemist for Quidd, a start-up
company developing in vivo optical imaging tools (www.quidd.com)
|
| <<
previous 20 |
|
If you want this page to be updated, please contact webmaster here
|
